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In a scene size-up, the primary focus is on assessing potential hazards. This step is crucial to ensure the safety of the paramedics, other emergency responders, and any individuals involved in the incident. By identifying and evaluating potential risks such as traffic, fire, unstable structures, or hazardous materials, responders can make informed decisions about how to approach the scene safely.

This assessment allows responders to implement necessary precautions before engaging with the situation, ensuring their own safety and that of others at the scene. While factors such as the extent of injuries, patient conditions, and medical history are important elements to consider later in the assessment and treatment process, they become relevant only after ensuring that the environment is safe to enter and work in. Thus, understanding the scene's hazards is a foundational step that significantly influences the overall response to the incident.